3. Bibliografía

Beskow C, Kanter L, Holgersson A, Nilsson B, Frankendal B, Avall-Lundqvist E, Lewensohn R. Expression of DNA damage response proteins and complete remission after radiotherapy of stage IB-IIA of cervical cancer. Br J Cancer. 2006; 94(11):1683-1689.

Bjork-Eriksson T, West C, Nilsson A, Magnusson B, Svensson M, Karlsson E, Slevin N, Lewensohn R, Mercke C. The immunohistochemical expression of DNA-PKCS and Ku (p70/p80) in head and neck cancers: relationships with radiosensitivity. Int J Radiat Oncol Biol Phys. 1999; 45(4):1005-1010.

Brown KD, Lataxes TA, Shangary S, Mannino JL, Giardina JF, Chen J, Baskaran R. Ionizing radiation exposure results in up-regulation of Ku70 via a p53/ataxia-telangiectasia-mutated protein-dependent mechanismJ Biol Chem. 2000; 275(9):6651-6656.

Friedberg EC.DNA damage and repair. Nature. 2003; 421(6921):436-437.

Grabsch H, Dattani M, Barker L, Maughan N, Maude K, Hansen O, Gabbert HE, Quirke P, Mueller W.Expression of DNA double-strand break repair proteins ATM and BRCA1 predicts survival in colorectal cancer. Clin Cancer Res. 2006; 12(5):1494-1500.

Gullo C, Au M, Feng G, Teoh G. The biology of Ku and its potential oncogenic role in cancer.Biochim Biophys Acta. 2006; 1765(2):223-234.

Harima Y, Sawada S, Miyazaki Y, Kin K, Ishihara H, Imamura M, Sougawa M, Shikata N, Ohnishi T. Expression of Ku80 in cervical cancer correlates with response to radiotherapy and survival. Am J Clin Oncol. 2003; 26(4):e80-5.

Leskov KS, Klokov DY, Li J, Kinsella TJ, Boothman DA. Synthesis and functional analyses of nuclear clusterin, a cell death protein. J Biol Chem. 2003 Mar 28;278(13):11590-600

Muller C, Paupert J, Monferran S, Salles B The double life of the Ku protein: facing the DNA breaks and the extracellular environment. Cell Cycle. 2005; 4(3):438-441.

Myung K, Ghosh G, Fattah FJ, Li G, Kim H, Dutia A, Pak E, Smith S, Hendrickson EA. Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86. Mol Cell Biol. 2004; 24(11):5050-5059.

Sakata K, Matsumoto Y, Tauchi H, Satoh M, Oouchi A, Nagakura H, Koito K, Hosoi Y, Suzuki N, Komatsu K, Hareyama M. Expression of genes involved in repair of DNA double-strand breaks in normal and tumor tissues.Int J Radiat Oncol Biol Phys. 2001; 49(1):161-167.

Sawada M, Sun W, Hayes P, Leskov K, Boothman DA, Matsuyama S. Ku70 suppresses the apoptotic translocation of Bax to mitochondria. Nat Cell Biol.

Kitahara O, Katagiri T, Tsunoda T, Harima Y, Nakamura Y. Classification of sensitivity or resistance of cervical cancers to ionizing radiation according to expression profiles of 62 genes selected by cDNA microarray analysis.Neoplasia. 2002; 4(4):295-303.

Koike M, Shiomi T, Koike A. Ku70 can translocate to the nucleus independent of Ku80 translocation and DNA-PK autophosphorylation. Biochem Biophys Res Commun. 2000; 276(3):1105-1111.

Komuro Y, Watanabe T, Hosoi Y, Matsumoto Y, Nakagawa K, Tsuno N, Kazama S, Kitayama J, Suzuki N, Nagawa H. The expression pattern of Ku correlates with tumor radiosensitivity and disease free survival in patients with rectal carcinoma. Cancer. 2002; 95 (6):1199-1205.

Korabiowska M, Voltmann J, Honig JF, Bortkiewicz P, Konig F, Cordon-Cardo C, Jenckel F, Ambrosch P, Fischer G Altered expression of DNA double-strand repair genes Ku70 and Ku80 in carcinomas of the oral cavity. Anticancer Res. 2006; 26(3A):2101-2105.

Lee KA, Kang JW, Shim JH, Kho CW, Park SG, Lee HG, Paik SG, Lim JS, Yoon DY. Protein profiling and identification of modulators regulated by human papillomavirus 16 E7 oncogene in HaCaT keratinocytes by proteomics. Gynecol Oncol. 2005; 99(1):142-152.

Lee SW, Cho KJ, Park JH, Kim SY, Nam SY, Lee BJ, Kim SB, Choi SH, Kim JH, Ahn SD, Shin SS, Choi EK, Yu E. Expressions of Ku70 and DNA-PKcs as prognostic indicators of local control in nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 2005; 62 (5):1451-1457.

2003; 5(4):320-329.

Saygili U, Gorkay IB, Koyuncuoglu M, Gol M, Uslu T, Erten O .The relationship between expression of Ku70 and survival in irradiated patients with endometrial carcinoma. Gynecol Oncol. 2004; 95(3):518-522.

Walker JR, Corpina RA, Goldberg J. Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair. Nature 2001; 412(6847):607-164.

Wilson CR, Davidson SE, Margison GP, Jackson SP, Hendry JH, West CM Expression of Ku70 correlates with survival in carcinoma of the cervix Br J Cancer. 2000; 83(12):1702-1706.

Zhao HJ, Hosoi Y, Miyachi H, Ishii K, Yoshida M,

Nemoto K, Takai Y, Yamada S, Suzuki N, Ono T

DNA-dependent protein kinase activity correlates

with Ku70 expression and radiation sensitivity in

esophageal cancer cell lines. Clin Cancer Res.
2000;
6(3):1073-1078.